Written by Helen M. Stanton on July 17, 2018
Xymogen Melatonin CR for Jet Lag

Xymogen Melatonin CR - Does It Work?-Review

What is Xymogen Melatonin CR?

Xymogen Melatonin CR is a supplement with the purpose of enhancing sleep, particularly for people who suffer from jetlag. It corrects the imbalance between the internal biological clock that controls the sleep cycle and the external clock which has stimuli such as changes in light levels and temperature. When the balance is reset, then the symptoms of jetlag such as insomnia and mood swings decrease. This review determines if this product is the best option to use when experiencing jet lag.

Ingredients & How It Works

  • Vitamin B6
  • Melatonin

Melatonin is the body's own hormone that is responsible for governing the cycle in our brain that determines whether we feel awake or sleepy. There are a number of things that can cause the brain to release this hormone. One of the things is decreasing light levels and temperatures. Another thing is stimulation from a different area of the brain which physically measures a 24-hour cycle. The 24-hour cycle normally syncs up with the environmental cues like light and temperature but this is not the case when a person has crossed a time zone. The person will release  melatonin at inappropriate times and will not release melatonin when they need it to fall asleep. Taking melatonin from a product such as this before falling asleep can help to re-establish the 24-hour cycle in that time zone.

Vitamin B6 increases levels of another chemical in the brain called gamma-aminobutyric acid which helps to support the effects of melatonin and promote sleepiness.

Daily Serving

One tablet of Xymogen Melatonin CR must be taken with water about 20 minutes before bedtime unless a healthcare practitioner advises differently. This provides a dosage of 10 mg  of vitamin B6 and 5 mg of melatonin.

The Cost

It seems the manufacturer does sell the product directly through their own website but they do not provide a price. The product is also sold on third party retailer websites. Currently, it is unavailable on the majority of these retailers though which means that the product has no more demand or the manufacturer is rebranding. But circumstances indicate that the product was not effective to begin with.


Returns are only available through the retailer of the product and not the manufacturer. This means that the manufacturer doesn't have their own stamp of confidence on the product. The guarantee is a stamp of confidence because it shows customers that the manufacturer accepts responsibility if the product does not work and is not simply trying to peddle a useless product.

Our Review Summary Of Xymogen Melatonin CR

This product contains a very good combination of ingredients with reasonable scientific basis for their inclusion. Unfortunately, there are a number of features of this product that are not ideal. The fact that it is not available raises is a huge red flag about how much customers previously thought of the product. The other major problem is that the manufacturer themselves does not express confidence in the product because they do not offer a guarantee. 

Well researched reviews, from the experts at Research & You.